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7-night Historic Mississippi River Cruise

Roundtrip New Orleans
7-night Historic Mississippi River Cruise
November 19, 2025
American Cruise Lines: American Serenade
Roundtrip New Orleans
Vacation Offer ID 1507124
Reference this number when contacting our travel specialist.
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Exclusive Offer
  • $100 per Couple Shipboard Credit
Overview
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Ship Info
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Staterooms
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Deckplans
The Signature Collection – Exclusive Amenities
The Signature Collection Sailings offer Exceptional Value and Exclusive Amenities.

Cruise Inclusions

  • Cruise
  • Meals
  • Entertainment and more
  • Destination Guide
  • Suggested Shore Excursions
Destination Arrival Departure
New Orleans

New Orleans 11/19/2025

New Orleans is a unique city rich in history and alive with tradition. Famed for its 17th-century architecture, culturally-inspired cuisine, and lively music, the rhythm of the city is as diverse as its people. Beginning your adventure in New Orleans will excite the senses as you explore the history of the French quarter, listen to spirited Jazz, and indulge in some local cuisine. A visit to the French Market, the country's oldest public market, is reminiscent of European markets, but in a tradition that is distinctively of New Orleans.,
11/19/2025 11/19/2025
Mississippi River Cruising

Mississippi River Cruising 11/20/2025

Board your ship and be treated to a Welcome Reception. Get to know your fellow guests and savor the view as you enjoy the afternoon rolling on the mighty Mississippi. Be entertained by onboard performers who will perform the music born of the river.
11/20/2025 11/20/2025
Houmas House

Houmas House 11/21/2025

Overlooking the Mississippi River, Natchez was first established as a French fort site in 1716, later becoming part of the United States as the first capital of Mississippi in 1817. Perched over 200 feet above the Mississippi River with 30-mile views along the river both north and south, the bluff of Natchez is a place to marvel the beauty and grandeur of the river. A quaint Southern town rich in culture and history, and known for its abundance of antebellum architecture, Natchez offers true southern hospitality with the attractions of a great small city.,
11/21/2025 11/21/2025
Oak Alley Plantation

Oak Alley Plantation 11/21/2025

Once serving as an antebellum sugar cane plantation, Oak Alley Plantation is rightfully named after its most distinguishing feature, a canopy of 300-year-old oak trees that form a quarter-mile path leading to the Mississippi River. Restored to its 19th-century grandeur, this classic Greek revival-style antebellum mansion is truly breathtaking.,
11/21/2025 11/21/2025
Baton Rouge

Baton Rouge 11/22/2025

Around every corner, U.S. history is alive in Vicksburg. This "Queen City of the Bluff" offers plenty of opportunities to take a step back in time. Civil war battlefields, century-old churches, cotton fields, and restored train depots are just a few of the many intriguing landmarks that await your visit. Marvel in the beautiful antebellum-style homes and watch Vicksburg's history come to life at the riverfront murals.,
11/22/2025 11/22/2025
Natchez

Natchez 11/23/2025

Established in 1809 and overlooking the Mississippi River, St. Francisville is a quaint Southern town that offers a glimpse into history. One of the largest shipping ports on the Mississippi River prior to the Civil War, St. Francisville is a small town with grand appeal. Experience this town's rich history as you tour historic plantations, including the famous Rosedown and The Myrtles, or explore the captivating gardens in this area.,
11/23/2025 11/23/2025
Vicksburg

Vicksburg 11/24/2025

Vicksburg is a place of drama. During the Civil War, the struggle to control Vicksburg proved to be a major turning point. The well-fortified connection between river and rail transportation was known as “The Gibraltar of the West.” A narrated exploration of the well-preserved National Military Park battlefield enlivens this powerful story and highlights its significance. President Abraham Lincoln summarized Vicksburg’s importance clearly when he said, “Vicksburg is the key. The war can never be brought to a close until that key is in our pocket… They can defy us from Vicksburg… As valuable as New Orleans will be to us, Vicksburg will be more so.” Several other excursion options are available, including exploring museums and historic sites with local expert guides or on your own. Walk aboard an enormous Army Corps of Engineers towboat. Stroll along the charming series of murals painted along the adjacent floodwall and read panels detailing the Vicksburg stories they illustrate.
11/24/2025 11/24/2025
Natchez

Natchez 11/24/2025

Vicksburg is a place of drama. During the Civil War, the struggle to control Vicksburg proved to be a major turning point. The well-fortified connection between river and rail transportation was known as “The Gibraltar of the West.” A narrated exploration of the well-preserved National Military Park battlefield enlivens this powerful story and highlights its significance. President Abraham Lincoln summarized Vicksburg’s importance clearly when he said, “Vicksburg is the key. The war can never be brought to a close until that key is in our pocket… They can defy us from Vicksburg… As valuable as New Orleans will be to us, Vicksburg will be more so.” Several other excursion options are available, including exploring museums and historic sites with local expert guides or on your own. Walk aboard an enormous Army Corps of Engineers towboat. Stroll along the charming series of murals painted along the adjacent floodwall and read panels detailing the Vicksburg stories they illustrate.
11/24/2025 11/24/2025
St. Francisville

St. Francisville 11/25/2025

As the bow-ramp from the ship opens and stretches to the shore, you will be welcomed into the historic cotton port of St. Francisville. Overlooking the river from atop a high, St. Francisville began as a part of Spanish West Florida in the early 1800s until American settlers overthrew the Spanish governing forces, and the region later became part of the United States. Experience this town’s rich history on your own or with a variety of guided excursions. As you explore, discover the Historic District which boasts magnificent mansions and unique boutique shops and admire cottonwood trees which transition to stately oaks adorned with Spanish moss.
11/25/2025 11/25/2025
New Orleans

New Orleans 11/26/2025

Welcome back to New Orleans, commonly referred to as the Birthplace of Jazz. There is something for everyone with this city's history, culture, and arts prevalent around every corner. The open-air artist colony proudly displays local artist's works on the iron fence in Jackson Square, while 45 museums carefully preserve city's rich history. Stay an extra day or even a few nights to enjoy this lively city.,
11/26/2025 11/26/2025
American Cruise Lines: American Serenade
American Cruise Lines is pleased to announce the American Serenade, one of the newest ships in the revolutionary modern riverboat series. The overture to American Serenade’s cruise season will begin on the legendary Mississippi River in 2023. Like her sister ship American Symphony, the 175-passenger American Serenade introduces an updated modern interior design, integrating an elegant and refined aesthetic with the tradition for the spacious comfort found aboard all of our ships. Drawing inspiration from the geography across America, the new interior design highlights natural textural elements and serene color palettes.
Ship Highlights
  • Ship features an on board fitness center and many spacious lounges where you can relax after the day’s adventures
  • Relax and unwind at Sundeck with beautiful views passing by
  • The Ship showcases panoramic views throughout, including an impressive four-story glass atrium in the center of the ship
Ship Statistics
Maiden Voyage
2023
Passenger Capacity
175
Number of Staterooms
91
Number of Suites
16
Wheelchair Accessible
Yes

Suite

Veranda Suite (Private Balcony) (VS) Call for pricing
Veranda Suite (Private Balcony)
  • Category: VS
  • Deck 4
With a generous 405 sq. ft. of relaxing space, each Veranda suite includes a private walk-out balcony to enjoy the panoramic views. Considered one of the finest staterooms on any cruise ship, guests will enjoy full-size bathrooms and large living area with sliding glass door.
Grand Suite (Private Balcony) (GS) Call for pricing
Grand Suite (Private Balcony)
  • Category: GS
  • Deck 4
The luxurious Grand Suite measures 650 sq. ft. and offers panoramic views through floor-to-ceiling glass windows. Sliding glass doors lead out to a private balcony complete with a private dining area, the perfect place to enjoy breakfast room service or watch the sun set. Each Grand Suite features a separate bedroom and living area, ideal for gathering with family and friends after an invigorating day of exploration.

Balcony

Single (Private Balcony) (SGB) Call for pricing
Single (Private Balcony)
  • Category: SGB
  • Deck 4
  • Deck 3
  • Deck 2
Perfect for the solo traveler, the Single staterooms offer all of the amenities you expect from a fine hotel. At 250 sq. ft., these staterooms have spacious bathrooms and large sliding glass doors that lead to a private balcony.
Balcony Stateroom (AAR) Call for pricing
Balcony Stateroom
  • Category: AAR
  • Deck 1
AAR staterooms on the main deck offer complete comfort with approximately 275 sq. ft. of living space. Enjoy a full-size bathroom, large picture window, and door leading out to a furnished private balcony. These staterooms also feature a large sitting area, ideal for getting together with friends.
Balcony Stateroom (AAM) Call for pricing
Balcony Stateroom
  • Category: AAM
  • Deck 3
Located on the third deck, these spacious staterooms feature commanding views of the passing river landscapes. At 350 sq. ft., there is plenty of room to enjoy the tasteful comfort of your surroundings. These staterooms have all the comforts of a fine hotel and feature floor-to-ceiling sliding glass doors with a private balcony to offer panoramic views from every angle.
Balcony Stateroom (AAC) Call for pricing
Balcony Stateroom
  • Category: AAC
  • Deck 2
AAC staterooms are conveniently located on the second deck and offer all of the comforts of a fine hotel. Complete with a private balcony and floor-to-ceiling sliding glass doors, these staterooms provide spectacular views of the surrounding landscape. At 316 sq. ft., these staterooms also offer a sitting area, desk and full-size bathrooms.
Prices are per person based on double occupancy. Pricing on some sailings may reflect special limited time offers, not combinable with any other offers/discounts. Valid on new bookings only.

All fares are quoted in US Dollars.

Deck 5

Stateroom Key

  • Grand Suite (Private Balcony) (GS)
  • Veranda Suite (Private Balcony) (VS)
  • Balcony Stateroom (AAM)
  • Balcony Stateroom (AAC)
  • Balcony Stateroom (AAR)
  • Single (Private Balcony) (SGB)
Deck 4

Stateroom Key

  • Grand Suite (Private Balcony) (GS)
  • Veranda Suite (Private Balcony) (VS)
  • Balcony Stateroom (AAM)
  • Balcony Stateroom (AAC)
  • Balcony Stateroom (AAR)
  • Single (Private Balcony) (SGB)
Deck 3

Stateroom Key

  • Grand Suite (Private Balcony) (GS)
  • Veranda Suite (Private Balcony) (VS)
  • Balcony Stateroom (AAM)
  • Balcony Stateroom (AAC)
  • Balcony Stateroom (AAR)
  • Single (Private Balcony) (SGB)
Deck 2

Stateroom Key

  • Grand Suite (Private Balcony) (GS)
  • Veranda Suite (Private Balcony) (VS)
  • Balcony Stateroom (AAM)
  • Balcony Stateroom (AAC)
  • Balcony Stateroom (AAR)
  • Single (Private Balcony) (SGB)
Deck 1

Stateroom Key

  • Grand Suite (Private Balcony) (GS)
  • Veranda Suite (Private Balcony) (VS)
  • Balcony Stateroom (AAM)
  • Balcony Stateroom (AAC)
  • Balcony Stateroom (AAR)
  • Single (Private Balcony) (SGB)